Lipase-catalyzed enantioselective esterification of flurbiprofen with n-butanol
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High Enantioselective Novozym 435-Catalyzed Esterification of (R,S)-Flurbiprofen Monitored with a Chiral Stationary Phase
Lipases form Candida rugosa and Candida antarctica were tested for their application in the enzymatic kinetic resolution of (R,S)-flurbiprofen by enantioselective esterification. Successful chromatographic separation with well-resolved peaks of (R)- and (S)-flurbiprofen and their esters was achieved in one run on chiral stationary phases by high-performance liquid chromatography (HPLC). In this...
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Transition-metal-catalyzed asymmetric synthesis is a powerful and commonly used method for preparing a wide range of enantiomerically pure compounds.1 Among organo-transition-metal compounds, Pd complexes have become indispensable tools for both common and stateof-the art organic synthesis.2 Although a large number of Pd-based catalytic systems have been developed for many kinds of reactions, P...
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ژورنال
عنوان ژورنال: Electronic Journal of Biotechnology
سال: 2000
ISSN: 0717-3458,0717-3458
DOI: 10.2225/vol3-issue3-fulltext-3